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Yes, the client uses the Bosh protocol for communication which is a standard protocol for communication between web clients and XMPP servers. Most existing XMPP servers support Bosh.

We have added however a few extensions to the Bosh implementation on both the Tigase client and the Tigase server side to improve communication, handle page reloads and so on. Therefore I think if setup of Tigase server and Tigase messenger would work best.